SCMNPs@Urea/Py-CuCl₂: a recyclable catalyst for the synthesis of pyrano[2,3-d]pyrimidinone and pyrano[2,3-d] pyrimidine-2,4,7-trione derivatives

Abstract

An efficient, simple, and mild strategy for the one-pot multicomponent synthesis of pyrano[2,3-d]pyrimidinone and pyrano[2,3-d]pyrimidine-2,4,7-trione derivatives is described using SCMNPs@Urea/Py-CuCl₂ nanoparticles as a reusable heterogeneous magnetic nanocatalyst. The catalyst was characterized using Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), vibrating sample magnetometry (VSM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and scanning electron microscopy (SEM). The SCMNPs@Urea/Py-CuCl₂ can be easily collected from the reaction solution by magnetic decantation using a permanent magnetic field and reused in six runs without significant decrease in catalytic activity.

Graphical Abstract

Keywords:

• SCMNPs@Urea/Py-CuCl2
• pyrano[2,3-d]pyrimidinone
• pyrano[2,3-d]pyrimidine-2,4,7-trione
• multicomponent synthesis
• magnetic nanocatalyst

Acknowledgement

This work was supported by National Natural Science Fund of China (No. 51762010), Guizhou Provincial High-level innovative talents (2015-4006).

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by National Natural Science Fund of China (No. 51762010), Guizhou Provincial High-level innovative talents (2015-4006).