Managing pregnancy in women with Sturge-Weber syndrome: case report and review of the literature

Abstract

Sturge-Weber syndrome (SWS) is a sporadic congenital neuro-cutaneous anomaly with capillary-venous malformation involving the brain, eye, and the ophthalmic division of the trigeminal nerve. In these cases, physiological changes in pregnancy, including hormonal and hemodynamic changes, may predispose to increased seizure frequency and even a life-threatening intracranial haemorrhage. There are only few case reports available about the management of women with pregnancy and SWS. We report two patients with SWS diagnosed in childhood and managed during pregnancy and reviewed the outcomes and complications during pregnancy in women with this disorder.

Keywords:

• Sturge-Weber syndrome
• pregnancy
• port-wine stain
• meningo-oculofacial angiomatosis
• phakomatosis

Ethical approval

Ethical approval was not sought because the details were retrieved from the records without collecting any identifying information. Patients provided written informed consent for publication in scientific journals.

Author contributions

AK, HS, JD, PPN, RA and ArK, conceived the idea and performed the search. VD, RA and JD collected the records and the images. AK, HS and VD and wrote the first draft. ArK, RA, PPN and JD reviewed and commented on the first draft. All authors contributed to revising and finalising the manuscript. AK (corresponding author) guarantees all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.

Disclosure statement

No potential conflict of interest was reported by the author(s).