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The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery
Volume 42, 2023 - Issue 6
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Case Report

Orbital manifestations of B-cell acute lymphoblastic leukemia/lymphoma

Jason C. Strawbridgea David Geffen School of Medicine, University of California, Los Angeles, California, USAORCID Iconhttps://orcid.org/0000-0001-9868-2270View further author information
ORCID Icon,
Kelsey A. Roelofsb Jules Stein Eye Institute, Division of Orbital and Ophthalmic Plastic Surgery, University of California, Los Angeles, California, USAView further author information
,
Jason Naderic Rosalind Franklin University School of Medicine, North Chicago, Illinois, USAView further author information
,
Tracie Y. Gohd Department of Pathology, University of California, Los Angeles, California, USAView further author information
&
Daniel B. Rootmanb Jules Stein Eye Institute, Division of Orbital and Ophthalmic Plastic Surgery, University of California, Los Angeles, California, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6911-1292View further author information
ORCID Icon
Pages 654-658 | Received 18 Mar 2022, Accepted 24 Apr 2022, Published online: 17 May 2022
 
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ABSTRACT

A 2-year-old boy presented with left periorbital edema, proptosis, hyperglobus and esotropia. Imaging revealed an inferotemporal orbital mass with adjacent bony erosion. Histological evaluation of an orbital biopsy revealed B-cell acute lymphoblastic leukemia/lymphoma (B-ALL/BLL). The patient was subsequently treated with chemotherapy. Although orbital involvement in acute myelogenous leukemia has been well-described, orbital manifestations of B-ALL/BLL are uncommon, with only a limited number of previous reports in the literature.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

Additional information

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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