The Hypoalgesic Effect of Low-Load Exercise to Failure Is Not Augmented by Blood Flow Restriction

ABSTRACT

Purpose: To 1) examine whether blood flow restriction would provide an additional exercise-induced hypoalgesic response at an upper and lower limb when it is incorporated with low-load resistance exercise until failure, and 2) examine if increases in blood pressure and discomfort, with blood flow restricted exercise, would mediate the exercise-induced hypoalgesia over exercise without blood flow restriction. Methods: Forty healthy young participants completed two trials: four sets of unilateral knee extension exercise to failure at 30% of one-repetition maximum, with and without blood flow restriction. Pressure pain thresholds were assessed before (twice) and 5-min post exercise at an upper and lower limb. Blood pressure and discomfort ratings were recorded to examine mediating effects on exercise-induced hypoalgesia with blood flow restricted exercise. Results: Pressure pain threshold increased following both exercise conditions compared to a control, without any differences between exercise conditions at the upper (exercise conditions vs. control: ~0.37 kg/cm²) and lower (exercise conditions vs. control: ~0.60 kg/cm²) limb. The total number of repetitions was lower for exercise with blood flow restriction compared to exercise alone [median difference (95% credible interval) of −27.0 (−29.8, −24.4) repetitions]. There were no mediating effects of changes in blood pressure, nor changes in discomfort, for the changes in pressure pain threshold at either the upper or lower limb. Conclusion: The addition of blood flow restriction to low-load exercise induces a similar hypoalgesic response to that of non-blood flow restricted exercise, with a fewer number of repetitions.

KEYWORDS:

• Blood flow restriction
• pain perception
• pain sensitivity
• pain threshold

Disclosure statement

No potential conflict of interest was reported by the author(s).

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/02701367.2022.2115443.

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Funding

No external sources of funding were used in the preparation of this article.