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Journal of Environmental Science and Health, Part B
Pesticides, Food Contaminants, and Agricultural Wastes
Volume 54, 2019 - Issue 10
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Articles

Controlled-release of fluazinam from biodegradable PLGA-based microspheres

Qi WangCollege of Life Science and Bioengineering, Beijing University of Technology, Beijing, P.R. China;
,
Mengfei ShenSchool of Materials Science and Engineering, State Key Lab of Metal Matrix Composites, Shanghai, P.R. China
,
Wenjing LiCollege of Life Science and Bioengineering, Beijing University of Technology, Beijing, P.R. China;
,
Wanwan LiSchool of Materials Science and Engineering, State Key Lab of Metal Matrix Composites, Shanghai, P.R. China
&
Fang ZhangCollege of Life Science and Bioengineering, Beijing University of Technology, Beijing, P.R. China; Correspondence[email protected]
Pages 810-816 | Published online: 02 Jul 2019
 
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Abstract

Pesticides are biological or chemical substances used to manage pests and diseases. Encapsulation of pesticides in biodegradable carriers creates a slow-release system that can improve water dispersibility and prolong residual activity. We prepared two kinds of poly (lactic-co-glycolic acid)(PLGA) nanoparticles (NPs) with polyvinyl alcohol (PVA) and sodium dodecyl sulfate (SDS) surfactants. These were used to encapsulate the fungicide fluazinam (Flu) against Rhizoctonia solani using the Shirasu Porous Glass (SPG) membrane emulsification method. Both nanoparticles had uniform spherical shapes with average diameters of 314.13 nm (SDS) and 612.80 nm (PVA). The slow-release microspheres had excellent sustained-release properties, resistance to UV degradation, storage stability, leaf surface coverage and antifungal efficacy compared to the commercial formulation.

Acknowledgement

The authors thank the National Key R&D Program of China (2016YFD0200502-2) for funding this study.

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