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Drug Metabolism Reviews Volume 51, 2019 - Issue 1
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Graphene nano-ribbon based high potential and efficiency for DNA, cancer therapy and drug delivery applications

Seyyed Mojtaba MousaviDepartment of Medical Nanotechnology School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; ;Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-3500-877X
ORCID Icon,
Sadaf SoroshniaDepartment of Chemical Engineering, University of Mohaghegh Ardabili (UMA), Ardabil, Iran; ORCID Iconhttp://orcid.org/0000-0003-1926-1406
ORCID Icon,
Seyyed Alireza HashemiDepartment of Medical Nanotechnology School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; ;Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; ORCID Iconhttp://orcid.org/0000-0002-4713-6883
ORCID Icon,
Aziz BabapoorDepartment of Chemical Engineering, University of Mohaghegh Ardabili (UMA), Ardabil, Iran; ORCID Iconhttp://orcid.org/0000-0003-4907-2462
ORCID Icon,
Younes GhasemiDepartment of Medical Nanotechnology School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; ORCID Iconhttp://orcid.org/0000-0003-4172-0672
ORCID Icon,
Amir SavardashtakiDepartment of Medical Biotechnology, Faculty of Advanced Medical Sciences and Technology, Shiraz, Iran
&
Ali Mohammad AmaniDepartment of Medical Nanotechnology School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran;
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Pages 91-104 | Received 14 Nov 2018, Accepted 11 Feb 2019, Published online: 03 May 2019
 
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Abstract

In this article, graphene oxide Nano ribbons (GONRs) and its high potential for using in medical fields have been reviewed. Recently, Graphene Nano ribbons (GNRs) has been a field of interest in biological methods and disease treatment such as drug delivery, DNA applications, and photothermal cancer therapies. GNRs demonstrate more efficient properties rather than other graphene-based Nanomaterials due to their larger surface area. These novel properties made them into a remarkable substitute material for biological fields as they have different cytotoxic effects and almost nontoxic to human health and the environment. In this study, some of the significant effects of GNRs such as Geno toxicity effects in human mesenchymal stem cells, DNA assembly, drug delivery agents, and the use of PEGylated GNRs in photothermal cancer therapy has been investigated.

Disclosure statement

No potential conflict of interest was reported by the authors.

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