Effect of Oyster Meat Preload on Postmeal Glycemic Control in Healthy Young Adults

Abstract

Objective: Evidence suggests that food preload improves postmeal glycemic profiles, but the effects of marine food are poorly understood. Our study aims to verify the regulating effects of premeal oyster meat (OM) on postprandial blood glucose.

Method: Edible parts of the flesh of oyster were prepared for a randomized crossover experiment. After overnight fasting, 20 healthy young men consumed 300 mL of preload drinks with 0 g/kg body weight (BW) (control), 0.1 g/kg BW, and 0.2 g/kg BW. Peripheral blood concentrations of glucose and gastrointestinal hormones were measured before preloading at baseline (0 minutes) and at intervals after the preload and after a preset rice meal. The nutrient composition of OM was analyzed.

Results: Compared with other doses, 0.2 g/kg BW OM preload induced higher plasma premeal insulin (p < 0.05), C-peptide (p < 0.05), and glucagon-like peptide-1 (GLP-1; p < 0.05) without altering the glucose concentrations during premeal times. By contrast, 0.2 g/kg BW OM induced less secretion of glucose (p < 0.05) and gastric inhibitory peptide (GIP; p < 0.05), but higher secretion of GLP-1 (p < 0.05) than 0.1 g/kg BW of OM after a meal. During the entire experiment (0–170 minutes), OM reduced the blood glucose (p < 0.05) and GIP (p < 0.05), but increased GLP-1 (p < 0.05). OM was rich in protein (78.4%) and low in fat (6%). Glutamic acid, aspartic acids, glycine, and taurine are the amino acids with high content found in OM.

Conclusions: OM preload reduces postmeal glycemia in healthy young people with associated changes in gastrointestinal hormone responses. This effect may be attributed to the rich contents of protein and amino acids of OM.

Keywords:

• Oyster meat
• preload
• hypoglycemia
• nutritional component
• gastrointestinal polypeptide

Author contributions

SL was responsible for designing the review protocol, writing the protocol and report, conducting the search, screening potentially eligible studies, extracting and analyzing data, interpreting results, and updating reference lists. GH was responsible for designing the review protocol and screening potentially eligible studies. He contributed to writing the report, extracting and analyzing data, and creating tables and figures. DL contributed to the design of the review protocol and writing the report. YT contributed to arbitrating potentially eligible studies, extracting and analyzing data, and interpreting results. ML contributed to data extraction and provided feedback on the report. FL contributed to extracting and analyzing data and interpreting results.

Disclosure statement

We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work.

Additional information

Funding

This work was supported by Natural Science Projects of Xiamen Medical College (K2016-38), Science and Technology Planning and Guiding Project of Xiamen City (3502Z20149021) originated by Xiamen Municipal Health and Family Planning Commission, Science and technology project of Fujian Education Department (JA14178), and the Scientific Research Foundation of Jimei University, China.