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Brief Report

Radiation Therapy for Primary Cutaneous Gamma Delta Lymphoma Prior to Stem Cell Transplantation

, , , ORCID Icon, , , , , , , , & ORCID Icon show all
Pages 263-270 | Received 15 Apr 2021, Accepted 16 Apr 2021, Published online: 31 Jan 2023
 

Abstract

We present a patient with widespread PCGD-TCL of the bilateral arms and legs, who underwent radiotherapy with 34 Gy in 17 fractions using circumferential VMAT and 3-D printed bolus to the four extremities prior to planned stem cell transplant, who was then found to have progression in the liver, lung, and skin, followed by drastic regression of all in and out-of-field lesions on imaging 1.5 months later. The cause of regression may be related to a radiation-induced abscopal effect from the immunomodulatory effects of radiation, or related to immune reactivation in the setting of cessation of systemic immunosuppressive agents.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

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