Seasonal facial erythema in a patient with allergic rhinitis treated using a combination of tranilast and roxithromycin

Abstract

Objective

A competitive effect with suppression of Th2 immune responses of the tranilast and roxithromycin combination is examined in an allergic rhinitis patient.

Patient and Methods

A 42-year-old female patient with allergic rhinitis caused by cedar pollen, which is one of the most common allergies during the spring, exhibited facial erythema with itching, particularly on both cheeks, and rhinitis symptoms, such as nasal discharge, and 200 mg/day of tranilast (original) and 300 mg/day of roxithromycin were administered.

Results

After 2 weeks, the patient’s skin lesions were mostly eliminated, with the skin appearing almost normal; itching was nearly absent; and rhinitis symptoms disappeared.

Conclusion

This combination may be a promising new therapeutic strategy for allergic rhinitis.

Keywords:

• Facial erythema
• allergic rhinitis
• tranilast
• roxithromycin

Correction Statement

This article has been corrected with minor changes. These changes do not impact the academic content of the article.

Acknowledgments

The author thanks Editage for English language editing.

Disclosure statement

No potential conflict of interest was reported by the author.

Additional information

Funding

The author reported there is no funding associated with the work featured in this article.