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Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 32, 2019 - Issue 1
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Case Studies

I-131 uptake in the breast from fat necrosis

Joseph T. HoangDepartment of Medicine, Texas A&M College of Medicine, Dallas, Texas; ORCID Iconhttp://orcid.org/0000-0002-2223-3150
, BS ORCID Icon,
Matthew R. WeissenbornDepartment of Radiology, Baylor University Medical Center at Dallas, Dallas, Texas; ORCID Iconhttp://orcid.org/0000-0003-4878-1187
, MD ORCID Icon,
Joseph J. SpigelDepartment of Radiology, Baylor University Medical Center at Dallas, Dallas, Texas;
, MD,
Brian J. WelchDepartment of Internal Medicine, Baylor University Medical Center at Dallas, Dallas, TexasORCID Iconhttp://orcid.org/0000-0003-2550-5454
, MD ORCID Icon &
Stanley J. GrossmanDepartment of Radiology, Baylor University Medical Center at Dallas, Dallas, Texas; Correspondence[email protected]
, MD
Pages 140-142 | Received 30 May 2018, Accepted 30 Aug 2018, Published online: 06 Feb 2019
 
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Abstract

Radioactive iodine I-131 whole-body scintigraphy is used to monitor thyroid cancer metastases after total thyroidectomy. We present a case of a woman who was diagnosed with papillary thyroid cancer and underwent a total thyroidectomy. I-131 scintigraphy revealed abnormal accumulation of radioactive iodine in the right breast causing concern for thyroid cancer metastasis. Mammographic studies confirmed that the abnormal radiotracer accumulation was due to fat necrosis in the breast. I-131 uptake in fat necrosis is a poorly understood process that is not clearly defined in the literature. This case highlights that false-positive uptake of I-131 can mimic metastases of thyroid carcinoma.

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