Tissue engineering to treat pelvic organ prolapse

Abstract

Pelvic organ prolapse (POP) is a frequent chronic illness, which seriously affects women's living quality. In recent years, tissue engineering has made superior progress in POP treatment, and biological scaffolds have received considerable attention. Nevertheless, pelvic floor reconstruction still faces severe challenges, including the construction of ideal scaffolds, the selection of optimal seed cells, and growth factors. This paper summarizes the recent progress of pelvic floor reconstruction in tissue engineering, and discusses the problems that need to be further considered and solved to provide references for the further development of this field.

Keywords:

• Pelvic organ prolapse
• scaffold
• seed cell
• growth factor
• tissue engineering

Disclosure statement

There are no conflicts to declare.

Additional information

Funding

This study was supported by the National Natural Science Foundation, China (grant no. 81572989) and the International Academic Cooperation Project of Science and Technology Committee of Shanghai, Shanghai, China (grant no. 18430721100).