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Review Articles

Posterior Herpetic Uveitis: A Comprehensive Review

, MD, , MD, , MD, , MD, , MDORCID Icon, , MD & , MD show all
Pages 1461-1472 | Received 11 Oct 2022, Accepted 30 May 2023, Published online: 26 Jun 2023
 

ABSTRACT

Purpose

To report and illustrate the main clinical presentations of posterior herpetic uveitis.

Methods

Narrative review.

Results

The ocular manifestations of posterior herpetic uveitis include different clinical presentations. Herpes simplex and varicella zoster can cause acute retinal necrosis, progressive outer retinal necrosis, and non-necrotizing herpetic retinopathies. Cytomegalovirus has been associated with fulminant retinitis with confluent areas of retinal necrosis and retinal hemorrhages, indolent/granular retinitis, and frosted branch angiitis. These diverse clinical presentations are often associated with specific risk factors and different immunological profiles of the host.

Conclusions

Herpetic viruses can cause posterior uveitis, presenting various clinical findings. Specific ocular manifestations and the immunological status of the host can help to differentiate the various herpetic entities before laboratory tests confirm the diagnosis.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

The author(s) reported that there is no funding associated with the work featured in this article.

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