Severe ovarian hyperstimulation syndrome induced by clomiphene: a case report

Abstract

This article reported a rare case of severe ovarian hyperstimulation syndrome (OHSS) following oral clomiphene. The patient was instructed to take clomiphene on the 5th day of menstruation, 50 mg daily for 5 days, without any medical examination or laboratory tests before administration of clomiphene. The treatment outcome was ideal by conservative treatment. This reminded that full assessment and risk prediction should be performed before the prescription of clomiphene. And clomiphene should be used only when indicated. What’s more, high risk factors of the particular patient should be taken into full consideration.

摘要

这篇文章报道了一例口服克罗米芬后导致罕见的严重卵巢过度刺激综合征(OHSS)。嘱患者月经第5天服用克罗米芬, 每天50mg, 连续服用5天, 用药前未做任何医学检查或实验室检查。经保守治疗, 治疗效果理想。提示在使用克罗米芬前应进行充分评估和风险预测。克罗米芬只能在有需要时应用。此外, 还应充分考虑特定患者的高危因素。

Keywords:

• Clomiphene
• severe ovarian hyperstimulation syndrome
• ovulation induction
• ovary

关键词:

• 克罗米芬
• 严重卵巢过度刺激综合征
• 促排卵
• 卵巢

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by Seed program of Beijing Friendship Hospital, Capital Medical University.