The impact of sleep duration on physical activity in daily life in patients with idiopathic pulmonary fibrosis

ABSTRACT

Background

Despite the high prevalence of sleep disturbances in idiopathic pulmonary fibrosis (IPF), the relationship between physical activity in daily life (PADL) and sleep in this population remains unclear

Objectives

Investigate the impact of sleep on different domains of PADL in IPF and characterize their PADL profile

Methods

Sixty-seven participants (thirty-three with IPF and thirty-four healthy subjects [control group]) were included. The subjects underwent assessments of pulmonary function, exercise capacity, respiratory and peripheral muscle strength, PADL, sleep, dyspnea, and health-related quality of life. PADL and sleep measures were assessed using an activity monitor (Actigraph®, wGT3x-BT). Associations between sleep and PADL were done using correlation and regression models.

Results

In the IPF, sleep duration at night associated significantly with step counts, sedentary, light, and moderate-to-vigorous physical activity (MVPA) (−0.82 ≤ R ≤ 0.43; p < .05 for all). Lung function and sleep partially explained PADL variables (0.19 ≤ R² ≤ 0.65, p < .05 for all). Compared to controls, the IPF subjects presented lower step counts, less time spent in MVPA, standing position, and more time spent in lying position (p < .05, for all)

Conclusions

Sleep duration is associated with PADL in IPF. The PADL profile of patients is worse than in control subjects.

KEYWORDS:

• Idiopathic pulmonary fibrosis
• sleep
• physical activity in daily life
• actigraphy

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was supported by the National Council for Scientific and Technological Development (CNPq/Brazil #426509/2018-8).