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Journal of Asian Natural Products Research Volume 21, 2019 - Issue 7
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A new menthane-type monoterpenoid from fermented Illigera aromatica with Clonostachys rogersoniana 828H2

Jian-Wei DongCollege of Chemistry and Environmental Science, Qujing Normal University, Qujing655011, China;Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming650091, ChinaORCID Iconhttp://orcid.org/0000-0002-0547-2870
ORCID Icon,
Le CaiFunctional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming650091, ChinaCorrespondence[email protected]
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Xue-Jiao LiCollege of Chemistry and Environmental Science, Qujing Normal University, Qujing655011, China;Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming650091, China
,
Ya-Xian ShiFunctional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming650091, China
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Jia-Peng WangFunctional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming650091, China
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Rui-Feng MeiFunctional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming650091, China
&
Zhong-Tao DingFunctional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming650091, ChinaCorrespondence[email protected]
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Pages 673-678 | Received 18 Dec 2017, Accepted 17 Apr 2018, Published online: 11 May 2018
 
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Abstract

A new menthane-type monoterpenoid, illigerate E (1), as well as two known ones, (1R*,3R*,4S*,6R*)-6,8-dihydroxymenthol (2) and cis-4-hydroxy-5-(1-hydroxy-1-methylethyl)-2-methyl-2-cyclohexene-1-one (3), were isolated from fermented Illigera aromatica with Clonostachys rogersoniana 828H2. Their structures were identified by HRESIMS and 1D/2D NMR spectra. Their inhibitory effects of NO production in RAW 264.7 macrophages were estimated.

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