309
Views
6
CrossRef citations to date
0
Altmetric
Articles

Triterpenoids with α-glucosidase inhibitory activity from Artemisia argyi

, , &
Pages 241-248 | Received 03 Sep 2018, Accepted 28 Oct 2018, Published online: 26 Dec 2018
 

Abstract

Two new nordammarane-type triterpenoids, 3β-acetoxy-20-oxo-21-nordammaran-23-carboxylic acid methyl ester (1) and 3β-acetoxy-17β-dammaranic acid (2), along with two known cycloartane-type triterpenoids (34), were isolated from the petroleum ether-soluble extract of Artemisia argyi. Their structures were elucidated based on 1D and 2D NMR spectroscopic data analysis. All compounds were evaluated for their α-glucosidase inhibitory activity in vitro. Compounds 14 exhibited significant inhibitory effects on α-glucosidase with IC50 values ranging from 38.34 ± 0.23 to 105.54 ± 0.33 μM.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Funding

This research was financially supported by grants from the National Natural Science Foundation of China [grant number 31400305 and 81773898] and the Project for Youth Backbone Teachers in the University of Henan Province [grant number 2015GGJS-130].

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 426.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.