Mannosylxylarinolide, a new 3,4-seco-ergostane-type steroidal saponin featuring a β-d-mannose from the endophytic fungus Xylaria sp.

Abstract

Mannosylxylarinolide (1), a new 3,4-seco-ergostane-type steroidal saponin featuring a β-d-mannose moiety, was isolated from the culture of the endophytic fungus Xylaria sp. that had been isolated from an ornamental plant of Hoya sp. The gross structure was determined by spectroscopic data, and the absolute configuration of the new 3,4-seco-ergostane-type steroidal saponin (1) was determined by X-ray diffraction analysis.

GRAPHICAL ABSTRACT

Keywords:

• Xylariaceae
• Xylaria sp.
• endophytic fungus
• mannosylxylarinolide

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The authors thank the Science and Technology Planning Project of Guangdong Province, China (Nos. 2013B020302006 and 2015A020211007), the National Natural Science Foundation of China (Nos. 81573302 and 81402813), and the Fundamental Research Funds for the Central Universities (No. 17ykzd12) for providing financial support to this work.