Two isopentenyl resorcinols from Peperomia tetraphylla

Abstract

Two isopentenyl resorcinols, peperobtusin B and peperobtusin C, have been isolated from Peperomia tetraphylla. Their structures were determined on the basis of spectroscopic methods, especially ¹H NMR, ¹³C NMR, 2D NMR, and HR-TOF-MS. Two compounds were evaluated for cytostatic activity against G₂, A 549, Hela and HCT 116 cells, but cytostatic activity of both compounds is weak.

Graphical abstract

Keywords:

• Piperaceae
• isopentenyl resorcinol
• Peperomia tetraphylla
• cytostatic activity

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by Liaoning BaiQianWan Talents Program, Scientific Research Funding Project of Liaoning Provincial Department of Education [grant number L2019604] and Dalian Youth Science and Technology Star Project Support Plan [grant number 2018RQ61].