Abstract
A new 4-hydroxy-α-pyrone, namely capsulactone (1), was isolated from an endophytic fungus Penicillium capsulatum XL027 obtained from the leaves of Panax notoginseng. The structure and absolute configuration of 1 were elucidated through a combination of spectroscopic data and computed methods, as well as by comparison with literature data. Compound 1 exhibited weak activity against methicinllin-resistant Staphylococcus aureus with an MIC value of 100 μg/ml.
Graphical Abstract
![](/cms/asset/9388572b-b693-4a50-939d-7a756f0502e6/ganp_a_1847092_uf0001_c.jpg)
Disclosure statement
No potential conflict of interest was reported by the authors.