Stenophyllols A-C, new compounds from Boesenbergia stenophylla

Abstract

Three new compounds, i.e. stenophyllols A-C (1-3), were isolated from the rhizome of Boesenbergia stenophylla. The structures were determined by spectroscopic analysis (UV, IR, NMR and HRESIMS). In-vitro neuroblastoma cell viability assay showed stenophyllol A (1) was able to reduce the N2A cell viability to 20% within 24 h.

Keywords:

• Zingiberaceae
• Boesenbergia stenophylla
• stenophyllol
• anti-neuroblastoma

Acknowledgements

We would like to thank Infra Laboratory Services, University of Malaya for the NMR and MS analysis. We would like to thank Madam Najmiyah Mohamad Alias, Delima Jelita Herbs Sdn. Bhd. for identification of plant material.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work has been supported by the University of Malaya Grant No. GPF055B-2018 and ST004-2018.