Advanced search
Publication Cover
Journal of Asian Natural Products Research Volume 24, 2022 - Issue 5
Submit an article Journal homepage
244
Views
1
CrossRef citations to date
0
Altmetric
Articles

Two new sesquiterpene dimers isolated from the roots of Saussurea lappa (Yunmuxiang)

Sheng-Tian Laia State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
,
Ting Zhangb Institute of Medical Information & Library, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100020, ChinaView further author information
,
Hong-Qing Wanga State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
,
Jun Xiea State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
,
Jian-Bo Liua State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
,
Ruo-Yun Chena State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaView further author information
&
Jie Kanga State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing100050, ChinaCorrespondence[email protected]
View further author information
 show all
Pages 490-495 | Received 18 Nov 2021, Accepted 30 Dec 2021, Published online: 24 Jan 2022
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

Two new sesquiterpene dimers, lappadimers A and B, were isolated from the roots of Saussurea lappa (Yunmuxiang). Their structures were established on the basis of spectroscopic methods. They were found to have potential anti-inflammatory activity at 10 µM and could reduce LPS-induced NO levels in murine macrophage, with inhibitory rates of 67% and 47%, respectively.

Graphical Abstract

Acknowledgments

We are grateful for the financial support from the CAMS Innovation Fund for Medical Sciences (CIFMS) (2021-I2M-1-028) and the Fund of Jiansheng Fresh Herb Medicine.

Declaration of competing interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Additional information

Funding

We are grateful for the financial support from the CAMS Innovation Fund for Medical Sciences (CIFMS) (2021-I2M-1-028) and the Fund of Jiansheng Fresh Herb Medicine.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 426.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.