Armatenols A–C, new antioxidant isoflavanols from Colutea armata

Abstract

Armatenols A–C (1–3), new isoflavan-4-ols, have been isolated from the CHCl₃-soluble sub-fraction of Colutea armata Hemsl. & Lace, along with two known compounds namely 8-methoxyvestitol (4) and colutequinone (5), reported for the first time from this species. Their structures have been elucidated through spectroscopic techniques including MS, IR, UV, CD, 1 D and 2 D NMR. Compounds 1–2 invariably showed significant antioxidant activity using the methods of 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity (DPPH), Fe³⁺ reducing antioxidant power (FRAP) assay and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) radical scavenging activity (ABTS).

Graphical Abstract

Keywords:

• Colutea armata
• Papilionaceae
• isoflavan-4-ols
• armatenols A–C
• antioxidant activity

Disclosure statement

No potential conflict of interest was reported by the author(s).