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Abstract
Investigation on the chemical components of Valeriana jatamansi Jones (Caprifoliaceae), a new lignan with pyran-ring, dipsalignan G (1), along with eight known compounds (2–9) were isolated. Their structures were elucidated by extensive analysis of 1D, 2D NMR and HR-ESI-MS spectroscopic data. Additionally, possible biosynthetic pathway of 1 was proposed. Finally, biological evaluation results showed that 8 had significant scavenging ability to ABTS and DPPH free radicals, with IC50 values of 1.35 ± 0.01 and 2.94 ± 0.01 μg/ml, respectively.
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Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This work was financially supported by the National Interdisciplinary Innovation Team of Traditional Chinese Medicine [NO.ZYYCXTD-D-202209], Sichuan Provincial Administration of Traditional Chinese Medicine [No. 2021MS476], Sichuan Science and Technology Program [NO. 2022NSFSC1303], Xinglin Scholar Research Promotion Project of Chengdu University of TCM (No. QJRC2022010), the Science and Technical Plan of Guangzhou (202102020828), and Natural Science Foundation of Guangxi Province of China (2018GXNSFAA281135).