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Abstract
Two new linear peptides, penicamides A and B (1 and 2), together with four known analogous were isolated from the extracts of the marine-derived fungus Penicillium sp. SCSIO 41512. Their structures were elucidated by analysis of 1D/2D NMR data and HRESI-MS. Their absolute configurations were established by Marfey’s methods and quantum chemical calculations.
Graphical Abstract
Acknowledgments
The authors also appreciate the analytical facility center (Z.H.X., A.J.S., Y.Z., X.M., X.H.Z.) of the South China Sea Institute of Oceanology, Chinese Academy of Sciences, for acquiring NMR, HRESIMS, experimental ECD data.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
The authors are grateful for the financial support provided by the Key Science and Technology Project of Hainan Province [ZDKJ202018], National Natural Science Foundation of China [82173709], Key-Area Research and Development Program of Guangdong Province [2020B1111030005], Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0406], and Institution of South China Sea Ecology and Environmental Engineering, Chinese Academy of Sciences [No.ISEE2021PY05].