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Abstract
Phytochemical analyses of Swertia davidii Franch. extracts using column chromatography and semi-preparative HPLC were performed. Two novel phenolic glycosides named swertiosides A and B (compounds 1 and 2, respectively) were isolated and characterized. Four known phenolic glycosides were also extracted (compounds 3-6). The structural characteristics of these novel compounds were analyzed using 1D, 2D NMR, and HRMS. All six compounds have never been isolated from this particular plant species before this study. Subsequent assessment of bioactive properties suggested that compounds 1 and 2 exhibited moderate levels of cytotoxicity.
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Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This work was supported financially by the Natural Science Key Research Program of Anhui Province University [KJ2019A0435], the Science and Technology Research Program of Chongqing Municipal Education Commission [KJZD-K202202701, KJQN202002710], and the Natural Science Major Project of Chongqing Three Gorges Medical College [XJ2021000301].