ABSTRACT
A new and efficient isocyanide-based one-pot multi-component reaction has been described for the synthesis of novel ?-spiroiminolactone derivatives. Products were obtained by a three-component condensation reaction between isocyanides with acetylenic esters which was trapped with 6H-indeno[1,2-b]pyrido[3,2-e]pyrazin-6-one (aromatic ketone) in CH2Cl2 without use of any catalyst or activator in excellent yields.
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Funding
We gratefully acknowledge financial support from the Research Council of the University of Sistan and Baluchestan and Islamic Azad University of yazd.