Topological Properties of Doxorubicin Conjugated PEG-PAsp Copolymer Molecular Structure Used in Cancer Treatment

Abstract

Numerous research suggest that the structural properties of chemical substances, medicines and their molecular structures have a clear inherent relationship. Among the different proposed systems, coupling a bioactive compound to a biocompatible polymer offers numerous points of interest, for example, better medication solubilization, better adjustment, explicit restriction and controlled discharge. Topological indices identified for such chemicals molecular structures may help researchers for better understand the physical characteristics, chemical reactions, and biological activity of the molecular materials. Therefore, the topological study of the chemical structures and medicines can cover for the lack of scientific experimentation and can offer a theoretical foundation for medication and pharmaceutical content manufacturing. Topological indices based on ev-degree and ve-degree are two novel degree-based indices as late represented in graph theory. In this paper, we have computed topological indices based on ev-degree and ve-degree for the Dox-loaded micelle comprising PEG-PAsp block copolymer bioconjugate molecular structure.

Keywords:

• Cancer drug
• Dox-conjugated PEG-b-polymeric (SP(m))
• ev-degree
• topological indices
• ve-degree

MATHEMATICS SUBJECT CLASSIFICATION:

• 05C09
• 05C92
• 92E10