Green Synthesis of Novel Azo-Linked 2-Aryl-quinazolinones Using of NiFe₂O₄@SP@GA Nanoparticle

Abstract

Amino glucose‐functionalized silica‐coated NiFe₂O₄ nanoparticles (NiFe₂O₄@SP@GA) were synthesized and characterized by X-ray powder diffraction, X-ray spectroscopy, transmission electron microscope, field emission scanning electron microscope, vibrating sample magnetometry, and Fourier transform infrared spectroscopy (FT-IR). NiFe₂O₄@SP@GA supply an eco-friendly procedure for the synthesis of some novel 2-aryl-quinazolinones through one-pot reaction of various synthetized azo-linked benzaldehyes, isatoic anhydride, and glycine in accordance with green chemistry rules. These compounds were obtained in high yields and short reaction times. The catalyst could be easily recovered and reused for six cycles with almost consistent activity. The structures of the synthesized azo-linked 2-aryl-quinazolinone compounds were confirmed by ¹H NMR, ¹³C NMR, and FT-IR spectral data and elemental analyses.

Graphical Abstract

Keywords:

• Green synthesis
• one-pot reaction
• 2-aryl-quinazolinones
• nanoparticles
• azo dyes

Acknowledgements

Financial support by Rasht Branch, Islamic Azad University is gratefully acknowledged.

Disclosure statement

There is no conflict of interest.