Abstract
Boric acid and pentaerythritol as a green and reusable catalytic system efficiently catalyzed the one-pot three-component synthesis of mono- and bis-pyrano[2,3-d]pyrimidinones, bis-alkylidene malononitriles, as well as spirooxindoles from the various aromatic aldehydes/isatins, malononitrile, and barbituric acid in water. Being environmentally friendly, reusability, short reaction times, high yields, low cost, commercial availability of the starting materials, and easy work-up are attractive features of the present work. 10 new compounds were synthesized in similar conditions reactions in high yields.
Acknowledgments
The authors are thankful to the Research Council of Shahrekord and Yazd University for their supports of this research.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Data availability statement
Research data are not shared.