Trio Role of Deep Eutectic Solvents in the Green Synthesis of 1,4-Dihydropyridine Synthesis via Hantzsch Reaction

Abstract

Here, we have reported a novel deep eutectic solvent (DES) with tremendous activity for the synthesis of dihydropyridines. DESs have played a trio role in the reaction. It acts as a green catalyst, solvent, and in-situ substrate in this chemical reaction. This method offers various advantages such as metal-free catalysis, green solvent, high yields of the products, and short reaction time.

Graphical Abstract

Keywords:

• Deep eutectic solvent
• green chemistry
• Hantzsch reaction
• 14-dihydropyridine
• metal free catalysis

Disclosure statement

No potential conflict of interest was reported by the authors.