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Review Articles

Surface-Enhanced Raman Spectroscopy and Electrochemistry: The Ultimate Chemical Sensing and Manipulation Combination

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Pages 110-134 | Published online: 18 Apr 2022
 

Abstract

One of the lessons we learned from the COVID-19 pandemic is that the need for ultrasensitive detection systems is now more critical than ever. While sensors’ sensitivity, portability, selectivity, and low cost are crucial, new ways to couple synergistic methods enable the highest performance levels. This review article critically discusses the synergetic combinations of optical and electrochemical methods. We also discuss three key application fields—energy, biomedicine, and environment. Finally, we selected the most promising approaches and examples, the open challenges in sensing, and ways to overcome them. We expect this work to set a clear reference for developing and understanding strategies, pros and cons of different combinations of electrochemical and optical sensors integrated into a single device.

Declaration of competing interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Additional information

Funding

The reported study was funded by RFBR and DFG, project number 21-53-12045, DFG project no. KA 1663/13-1.

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