Microwave-assisted synthesis of α-aminophosphine oxides

Abstract

Aminophosphine oxides and bis(phosphinoylmethyl)amines were synthesized by the microwave (MW)-assisted Kabachnik-Fields reaction of primary amines, paraformaldehyde and secondary phosphine oxides. The bisphosphines obtained after deoxygenation of the bis(phosphinoymethyl)amine derivatives were utilized in the synthesis of cyclic transition metal complexes.

GRAPHICAL ABSTRACT

Keywords:

• Kabachnik–Fields reaction
• microwave
• α-aminophosphine oxides
• transition metal complexes

Acknowledgments

The project was supported by the Hungarian Research Development and Innovation Fund (FK123961 and K119202). The authors thank for Prof. László Kollár and Dr. Péter Pongrácz to testing the platina complexes synthesized in the hydroformylation of styrene.