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Phosphorus, Sulfur, and Silicon and the Related Elements Volume 196, 2021 - Issue 1
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Research Article

A new highly sensitive and selective fluorescent probe for Hg2+ and its application in living cells

Mengsheng Xua College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, China;b Henan Cereal Quality and Safety Testing Key Laboratory, Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaView further author information
,
Le Wanga College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, ChinaCorrespondence[email protected] [email protected]
View further author information
,
Man Lib Henan Cereal Quality and Safety Testing Key Laboratory, Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaView further author information
,
Zhiwei Mab Henan Cereal Quality and Safety Testing Key Laboratory, Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaView further author information
,
Di Zhangb Henan Cereal Quality and Safety Testing Key Laboratory, Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaCorrespondence[email protected] [email protected]
View further author information
&
Jihong Liub Henan Cereal Quality and Safety Testing Key Laboratory, Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaView further author information
Pages 13-18 | Received 03 May 2020, Accepted 18 Jul 2020, Published online: 10 Aug 2020
 
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Abstract

A new coumarin-based probe (HgP) with two “S” groups was designed and synthesized The probe HgP exhibited a fast response time (<2 min) and high selectivity (DL, 2.2 × 10−7 mol/L). Furthermore, its capability of biological application was stu died, and the results showed that it could be applied to recognize Hg2+ in living cells (HK2 cells).

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Funding

This work was financially supported by the Independent Innovation Project of Henan Academy of Agricultural Sciences (2018ZC68), Scientific and Technological Project of Henan Province of China (192102310140), Scientific and Technological Innovation Project of Henan Academy of Agricultural Sciences (2020CX05), and Starting funds for postdoctoral research projects in Henan Province (201900119).

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