Potential conflict of interest
Disclosure forms provided by the authors are available with the full text of this article online at https://doi.org/10.1080/10428194.2019.1627542.
Author contributions
E.L. and I.K. wrote the manuscript; E.Z. and C.K. drafted the manuscript and processed patient data and samples; E.P and E.B. performed NGS studies; M.P., Z.B. and G.V. managed the patients and collected data and samples; all authors approved the final manuscript.
Acknowledgments
EP is an EHA Fellow an ASH Scholar and a Josie Robertson Investigator. EP received research support from the MDS Foundation. EB is supported by the Francois Wallace Monahan Fellowship.