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Research Article

Phytochemicals, Antihemolytic, Anti-inflammatory, Antioxidant, and Antibacterial Activities from Thymus Algeriensis

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Pages 253-266 | Received 07 Feb 2020, Published online: 12 Mar 2021
 

ABSTRACT

The chemical composition and anti-inflammatory, antihemolytic, antioxidant, and antibacterial activities of solvent extracts of Thymus algeriensis in petroleum ether, chloroform, and n-butanol were evaluated. Ten compounds including four flavonoids, four phenolics, and two triterpenoids were isolated and identified by chromatography and spectroscopy. The n-butanol extract had the greatest antioxidant activity and inhibited hemolysis with a value of IC50 at 322.85 ± 0.87 µg mL−1. The chloroform extract exhibited the highest anti-inflammatory effect with 45.27% inhibition. The extracts demonstrated antibacterial activity against the tested strains.

Acknowledgments

The authors are grateful to the DGRSDT and the Ministry of Higher Education and Scientific Research of Algeria for PRFU Project (B00L01UN050120180001), and the team of Natural Substances Chemistry, Institute of Molecular Chemistry, Reims (ICMR) - UMR CNRS 7312, Reims University France for providing technical support.

Disclosure Statement

No potential conflict of interest was reported by the authors.

Supplementary Material

Supplemental data for this article can be accessed on the publisher’s website

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