ABSTRACT
Objective
To evaluate the diagnostic performance of Doppler sonography of umbilical artery (UA), fetal middle cerebral artery (MCA), ductus venosus (DV) & umbilical vein (UV) for prediction of adverse perinatal outcome.
Material and Methods
A prospective cohort study conducted on 60 women diagnosed with preeclampsia with severe features divided into two groups based on adverse perinatal outcome.
Results
Statistically Significant differences were demonstrated UA PI (1.28 ± 0.23 vs. 0.96 ± 0.21, P <0.001), UA RI (0.78 ± 0.09 vs. 0.62 ± 0.09, P <0.001), MCA PI (1.27 ± 0.28 vs. 1.45±0.20, P 0.005), MCA RI (0.67 ± 0.10 vs. 0.76 ± 0.08, P<0.001), Cerebroplacental ratio (1.01 ± 0.36 vs. 1.57 ± 0.35, P <0.001), DV PVIV (0.67 ± 0.20 vs. 0.51 ± 0.14, P= 0.004), DV PSV (54.74 ± 17.11 vs. 42.15 ± 9.42, P= 0.004) and abnormal DV a wave (23.8 vs. 0%, P = 0.004) in women with adverse and normal perinatal outcome respectively. UA PI and CPR had the highest specificity while UA RI had the highest sensitivity for detection of adverse perinatal outcome.
Conclusion
CPR < 1 can be used to identify fetuses at risk of morbidity and mortality among such cases.
Author contributions
Nihal M. El-Demiry: Data collection, manuscript writing.
Ahmed M Maged: Project development, manuscript writing.
Hassan M Gaafar: Data collection, manuscript writing.
Sherif ElAnwary: Data collection, manuscript writing.
Amany Shaltout: Data reanalysis, manuscript revision.
Safaa Ibrahim: Data reanalysis, manuscript revision.
Hany Eldidy: Data collection, manuscript writing.
Moutaz Elsherbini: Data collection, manuscript writing.
Compliance with ethical standards
The study was performed in accordance with the Declaration of Helsinki ethical standards. Informed consents were taken from study participants.
Disclosure statement
The authors report no conflicts of interest in this work.