ABSTRACT
Objective
This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE).
Methods
Serum apelin, galectin-3, and insulin levels were measured in 60 PE women and 30 normotensive pregnant.
Results
The PE group had significantly lower apelin and higher galectin-3 levels than the control group. PE group exhibited dyslipidemia and had higher β-cell functions than the controls. Galectin-3 level correlates with insulin, glucose, and IR. High galectin-3 also is correlated positively with dyslipidemia.
Conclusion
In PE, there is a possible contribution of galectin-3 to the harmful effects of IR and dyslipidemia.
Acknowledgments
We are grateful to the University of Kashan for supporting this work.
Disclosure statement
The authors have no conflict of interest with any commercial or other association in connection with the submitted article.