Relationship of sleep duration on workdays and non-workdays with blood pressure components in Chinese hypertensive patients

ABSTRACT

Objectives: This study aimed to assess the relationship of sleep duration on workdays and non-workdays with BP components [systolic BP (SBP), diastolic (DBP), pulse pressure (PP), and mean arterial pressure (MAP)] among Chinese hypertensive adults.

Methods: The study included 3,376 hypertensive patients without antihypertensive treatment. Self-reported sleep durations on workdays and non-workdays were measured by the questionnaire. Multiple linear regression analyses were performed to evaluate the association of sleep duration with BP components.

Results: Overall, compared with a sleep duration of 5–9 h, individuals who slept ≥10 h on both workdays and non-workdays were positively correlated with SBP [β (95% CIs) = 3.99 (1.06, 6.93) and 4.33 (1.79, 6.87)] and PP [β (95% CIs) = 3.25 (0.71, 5.79) and 3.05 (0.85, 5.25)], but not with DBP. Moreover, individuals who slept ≥10 h only on non-workdays had higher MAP [β (95% CIs) = 2.30 (0.63, 3.97)]. The stratified analyses showed that subjects with a BMI ≥24 kg/m² in the longer sleep duration group (≥10 h) only on workdays compared to the reference group had higher SBP, DBP and MAP (all P for interaction <0.05). The effect of longer sleep duration on BP components showed no difference in the following subgroups: sex, age, smoking and drinking (all P for interaction >0.05).

Conclusion: Compared with a sleep duration of 5–9 h, longer sleep duration (≥10 h) on workdays and non-workdays was associated with high SBP and PP among Chinese hypertensive adults without antihypertensive treatment.

KEYWORDS:

• Sleep duration
• workdays
• non-workdays
• blood pressure components
• hypertensive adults

Acknowledgments

We acknowledge the contribution the all staff who participated in this study as well as the study participants who shared their time with us. This work was supported by the National Key R&D Program in the Twelfth Five-year Plan (No. 2011BAI11B01, and 2014ZX09303305) from the Chinese Ministry of Science and Technology and National Natural Science Foundation of China (No.81260023, and 81560051).

Disclosure Statement

The authors report no conflicts of interest.

Supplementary material

Supplementary data can be accessed here

Additional information

Funding

This research was supported by the National Key R&D Program in the Twelfth Five-year Plan (No. 2011BAI11B01, and 2014ZX09303305) from the Chinese Ministry of Science and Technology and National Natural Science Foundation of China (No. 81260023, and 81560051).