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Biomarkers Volume 27, 2022 - Issue 6
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Article Commentaries

Commentary: statistical analysis of 2 × 2 tables in biomarker studies 2) study design and statistical tests

David Paul LovellPopulation Health Research Institute (PHRI), St George’s Medical School, University of London, Tooting, LondonSW17 0RE, United KingdomCorrespondence[email protected]
Pages 512-519 | Received 24 Mar 2022, Accepted 29 May 2022, Published online: 31 Aug 2022
 
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Abstract

In this article the importance of study design will be emphasized, statistical methods for analysing the data are described and some of the implications of these method are discussed. How these issues relate to the use of SpIN and SnOUT rules are reviewed.

Funding

The author reported there is no funding associated with the work featured in this article.

Data availability statement

No data deposited. Data in Box 1 available in McCann and Ames paper.

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