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Review Articles

Vertical transmission of SARS CoV-2: a systematic review

ORCID Icon & ORCID Icon
Pages 2655-2662 | Received 14 Jun 2020, Accepted 05 Jul 2020, Published online: 21 Jul 2020
 

Abstract

Objective

The aim of this study is to review the current evidence on the vertical transmission of SARS CoV-2.

Methods

Combination of the following keywords; COVID-19, SARS CoV-2, placenta, vertical transmission, intrauterine infection, breast milk were searched in databases.

Results

In the 50 studies included, 17 newborns testing positive for SARS CoV-2 by RT-PCR were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated. Eight placental tissues testing positive for the virus were reported. Three positive RT-PCR results of test of breast milk have been reported recently. One amniotic fluid testing positive was reported.

Conclusion

Possible vertical transmission of SARS CoV-2 has been observed in some studies currently. More RT-PCR tests on amniotic fluid, placenta, breast milk and cord blood are required.

Disclosure statement

No potential conflict of interest was reported by the author(s).

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