Laceioside, a new cycloartane saponin from Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff.

Abstract

Phytochemical investigation of the aerial parts of Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff. (Family Fabaceae) resulted in the isolation of a new cycloartane glycoside laceioside (1). The structure of the previously undescribed compound 1 was established as 16β-acetyloxy-3-O-β-d-glucopyranosyloxy-cycloartan-11α,24ξ, 25-triol. The structure elucidation of compound 1 was based primarily on 1D and 2D-NMR techniques including ¹H and ¹³CNMR spectra, DEPT and by 2D COSY, HSQC and HMBC experiments.

Keywords:

• Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff.
• Fabaceae
• cycloartane triterpenoid glycoside

Acknowledgements

A Post Doctoral Fellowship to one of us (FVM) by Pakistan Academy of Sciences is gratefully acknowledged.