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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 3
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Research Articles

New dihydrophenanthrenes from Dendrobium infundibulum

Salinee Na RanongFaculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany, Chulalongkorn University, Bangkok, Thailand
,
Kittisak LikhitwitayawuidFaculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany, Chulalongkorn University, Bangkok, Thailand
,
Wanwimon MekboonsonglarpScientific and Technological Research Equipment Centre Chulalongkorn University, Bangkok, Thailand
&
Boonchoo SritularakFaculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany, Chulalongkorn University, Bangkok, Thailand;Natural Products for Ageing and Chronic Diseases Research Unit, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, ThailandCorrespondence[email protected]
Pages 420-426 | Received 09 Feb 2018, Accepted 17 Mar 2018, Published online: 23 Mar 2018
 
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Abstract

Two new dihydrophenanthrenes, dendroinfundin A (1) and dendroinfundin B (2) were isolated from the whole plant of Dendrobium infundibulum, together with 7 known compounds (3–9). The structures of the new compounds (1 and 2) were established on the basis of their spectroscopic data. All of the isolates were evaluated for their α-glucosidase and pancreatic lipase inhibitory activities. Batatasin III (5) and dendrosinen B (9) showed strong α-glucosidase inhibitory activity. Dendrosinen B (9) also exhibited appreciable pancreatic lipase inhibitory effect.

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