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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 19
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Research Articles

Two new triterpenoids from Gardenia jasminoides fruits

Dan LuInstitute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou, People’s Republic of China; View further author information
,
Weiyang ZhangFaculty of Chinese Medicine, Macau University of Science and Technology and State Key Laboratory of Quality Research in Chinese Medicine, Taipa, Macau, People’s Republic of ChinaView further author information
,
Yingnan JiangCollege of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China; View further author information
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Yu ZhangInstitute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou, People’s Republic of China; View further author information
,
Dabo PanInstitute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou, People’s Republic of China; View further author information
,
Dan ZhangInstitute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; View further author information
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Xinsheng YaoInstitute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou, People’s Republic of China; Correspondence[email protected]
View further author information
&
Yang YuInstitute of Traditional Chinese Medicine & Natural Products, College of Pharmacy and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research, Jinan University, Guangzhou, People’s Republic of China; Correspondence[email protected]
View further author information
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Pages 2789-2794 | Received 11 Mar 2018, Accepted 12 Jul 2018, Published online: 05 Dec 2018
 
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Abstract

A new cycloartane triterpenoid, named gardenolic acid C (1), a new ursane triterpenoid, named 3β,16β,21β,23,24-pentahydroxy urs-12,18,20-trien-28-oic acid γ-lactone (2), together with three know triterpenoids, gardenolic acid A (3), gardenolic acid B (4), and 3α,16β,23,24-tetrahydroxy-28-nor-ursane-12,17,19,21-tetraen (5) were isolated from the fruits of Gardenia jasminoides Ellis. The structures of these compounds were elucidated by analyses of spectroscopic data. All isolates were evaluated for their neuroprotective effects in vitro.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the National Natural Science Foundation of China [grant number 81630097], [grant number 81602984].

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