Abstract
A new oleanane triterpenoid (2) was isolated from the roots of Rubia philippinensis. The structure of 2 was determined by analysis of HRMS and NMR data and identified as a rubiprasin analogue, 16β-hydroxyrubiprasin B. Four related known compounds were also encountered which include rubiprasin B (1), maslinic acid (3), 4-epi-hederagenin (4) and oleanolic acid (5). The compounds 3–5 displayed moderate inhibitory activity against the synthesis of the eicosanoid 20-HETE.
Graphical Abstract
![](/cms/asset/746b43cf-fdb2-466e-914f-6da5351fcb40/gnpl_a_1645656_uf0001_c.jpg)
Disclosure statement
No potential conflict of interest was reported by the authors.