https://orcid.org/0000-0001-8010-0682
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Abstract
A new unsaturated fatty acid (E)-7,9-diene-11-carbonyl stearic acid (1) and a new lignan 8′-acetyl olivil (2), together with 14 known compounds (3–16), were isolated from the stem of Urtica fissa E. Pritz. Their structures were elucidated by spectroscopic and mass-spectrometric analyses. 8′-Acetyl olivil (2), (6 R,9R)-roseoside (15) and urticol-7-O-β-d-glucopyrannoside (16) exhibited significant inhibition on α-glucosidase activities, with IC50 values less than 9 μM.
Graphical Abstract
Acknowledgements
The authors thank Dr. Bona Dai and Guan Gui of the Instrumental Analysis Center of Shanghai Jiao Tong University for the measurements of NMR and MS spectra, respectively.
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This study was supported by grant from the National Natural Science Foundation of China (No. 81374067) and Shanghai Municipal Commission of Health and Family Planning (2018ZY002).