Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 18
Submit an article Journal homepage
242
Views
4
CrossRef citations to date
0
Altmetric
Short Communications

A new monoterpene-lactone with neuroprotective activity from corn silk

Wei-Yu Zhoua Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, ChinaView further author information
,
Tian-Ming Lva Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, ChinaView further author information
,
Zi-Lin Houa Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, ChinaView further author information
,
Ming Baia Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, ChinaView further author information
,
Bin Linb School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, People’s Republic of ChinaView further author information
,
Xiao-Xiao Huanga Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, ChinaCorrespondence[email protected]
View further author information
&
Shao-Jiang Songa Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, ChinaView further author information
 show all
Pages 3142-3145 | Received 20 Sep 2019, Accepted 29 Oct 2019, Published online: 11 Nov 2019
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

A new monoterpene-lactone (1) along with five known compounds (2–6) were isolated from corn silk. The structure of the new compound was elucidated based on comprehensive spectroscopic analyses and quantum chemical calculations of electronic circular dichroism (ECD) curves. All compounds were evaluated for their neuroprotective effects against H2O2-induced damage in human dopaminergic neuroblastoma cells (SH-SY5Y). As a result, compound 1 exhibited weak neuroprotective activity.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by Career Development Support Plan for Young and Middle-aged Teachers in Shenyang Pharmaceutical University (ZQN2018006) and the Project of Innovation Team Foundation (LT2015027).

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 861.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.