Abstract
A new phenylpentenol, wortmannine H (1) was isolated from Talaromyces wortmannii LGT-4, an endophytic fungus of Tripterygium wilfordii. The structure of 1 was elucidated by IR, MS, 1D and 2D NMR spectra and comparison of the experimental and calculated optical rotatory dispersion (ORD). Monoamine oxidase (MAO), acetylcholinesterase (AChE) and phosphoinositide 3-kinase (PI3Kα) inhibitory activities of 1 was also tested. The compound did not show good biological activity.
Graphical Abstract
![](/cms/asset/0d67a862-6fd4-498a-a802-c8d8e6d67cac/gnpl_a_1690488_uf0001_c.jpg)
Disclosure statement
No potential conflict of interest was reported by the authors.