New acetylenic metabolites from the toxic mushroom Tricholoma pardinum

Abstract

Four unprecedented acetylenic alcohols, (Z)-non-7-en-5-yn-1,2,4-triol (1), (Z)-non-7-en-5-yn-1,4-diol (2), (Z)-1,2-dihydroxynon-7-en-5-yn-4-one (3), and (Z)-1-hydroxynon-7-en-5-yn-4-one (4) were isolated from the poisonous mushroom Tricholoma pardinum (Agaricales, Basidiomycota), together with the known compounds 1H-indole-3-carbaldehyde (5) and 6-hydroxy-1H-indole-3-carbaldehyde (6). Their structures were determined by NMR and IR spectroscopy, and mass spectrometry. The crude acetone extract of the mushroom showed potent anti-arthropod activity against Tetranychus urticae (Acarinae), a dangerous crop pest.

Keywords:

• Fungi
• Tricholoma
• acetylenic metabolites
• anti-arthropod activity
• Tetranychus urticae

Disclosure statement

The authors declare that there is no conflict of interests.

Additional information

Funding

This work was financially supported by Tishk International University, Erbil, Iraq, and by the Università del Piemonte Orientale (UPO), according to the Cultural Co-operation Framework Memorandum of Understanding between the two Institutions. R. Pavela would like to thank the Ministry of Agriculture of the Czech Republic for its financial support concerning botanical pesticide research (Project MZE-RO0418).