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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 2
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Research Articles

A new ceramide from the leaves of Lannea schimperi (Hochst. ex A.Rich.) Engl.

Rolande Tsafack Nguemoa Department of Chemistry, University of Dschang, Dschang, CameroonView further author information
,
Roukayatou Mbouangouerea Department of Chemistry, University of Dschang, Dschang, CameroonCorrespondence[email protected]
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Gabin Thierry M. Bitchagnoa Department of Chemistry, University of Dschang, Dschang, Cameroon;b Institute of Organic Chemistry, Johannes Gutemberg-University of Mainz, Mainz, GermanyCorrespondence[email protected]
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Roland Tchuenguemc Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, CameroonView further author information
,
Elise Vanessa N. Temgouaa Department of Chemistry, University of Dschang, Dschang, CameroonView further author information
,
Blanche Laure Ndontsaa Department of Chemistry, University of Dschang, Dschang, CameroonView further author information
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James Simo Mpetgaa Department of Chemistry, University of Dschang, Dschang, CameroonView further author information
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Till Opatzb Institute of Organic Chemistry, Johannes Gutemberg-University of Mainz, Mainz, GermanyView further author information
,
Augustin Silvere Ngouelaa Department of Chemistry, University of Dschang, Dschang, CameroonView further author information
&
Pierre Tanea Department of Chemistry, University of Dschang, Dschang, CameroonView further author information
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Pages 515-522 | Received 22 Mar 2020, Accepted 23 Jun 2020, Published online: 06 Jul 2020
 
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Abstract

A new ceramide is being reported herein together with six known compounds from the methanol extract of the leaves of Lannea schimperi (Hochst. ex A.Rich.) Engl. The metabolites were obtained through repeated open column chromatography and were characterized by spectroscopic and spectrometric techniques. The radical-scavenging activity of the crude extract and isolated compounds was evaluated using the DPPH radical. The obtained results suggest the studied species as prominent candidate to fight reactive oxygen species (ROS).

Disclosure statement

The authors declare that they have no competing interests.

Additional information

Funding

GTBM is grateful to the German Academic Exchange Service (DAAD) (57381410) and the Institute for Organic Chemistry of the University Johannes Gutenberg of Mainz for financial support.

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