https://orcid.org/0000-0001-9891-4326
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Abstract
A new diterpenoid, phyllane C (1), along with three known compounds, ovoideal E (2), spruceanol (3), and fluacinoid B (4) were isolated from the leaves of Phyllanthus acidus growing in Thailand. The structures were determined by analysis of their MS and NMR data as well as by comparison with literature values. DFT-NMR chemical shift calculations and subsequent DP4/DP4+ probability methods were applied to define the relative configuration of 1. Compound 3 showed a weak cytotoxicity against K562 cell line (IC50 41.9 ± 2.31 µg/mL).
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Correction Statement
This article has been republished with minor changes. These changes do not impact the academic content of the article.
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Funding
The authors gratefully acknowledge the financial support provided by Faculty of Science and Technology, Contract No. SciGR27/2563. Chemical and equipment support from Thammasat University Research Unit in Natural Products Chemistry and Bioactivities, Thammasat University, is gratefully acknowledged.